Research articles and papers

Acid Reflux / Hiatus Hernia

Hiatus hernia and gastroesophageal reflux disease as a manifestation of a newly revealed hypothyroidism
Savina LV, Semenikhina TM, Korochanskaia NV, Klitinskaia IS, Iakovenko MS.
Klin Med (Mosk). 2006;84(2):71-4.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/16613012

Adrenals

Glucocorticoids for the treatment of post-traumatic stress disorder and phobias: therapeutic approach
de Quervain DJ, Margraf J.
Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8032 Zürich, Switzerland. quervain@bli.unizh.ch
Eur J Pharmacol. 2008 Apr 7;583(2-3):365-71. Epub 2008 Jan 24.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18275950

Is there a Thyroid-Cortisol -Depression Axis?
Frank King Thompson, Director, Fallbrook Medical Research Foundation.
2414 Via La Orilla, Fallbrook, CA 92028, USA.
Summarised from: Thyroid Science 2(10)1, 2007.
To see the abstract of this article go to: http://www.thyroidscience.com/hypotheses/thompson.2007/F.K.Thompson.thyroid-cortisol-depression%20axis.httm

Chronic Stress at work and the metabolic syndrome: prospective study
Tarani Chandola, Eric Brunner, Michael Marmot.
BMJ,doi:10.1136/bmj.38693.435301.80 (pub 20 Jan 2006)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16428252

Misinterpretation of serum cortisol in a patient with hyponatraemia
Jamie C Smith, H Siddique, R J M Corrall.
Dept. of Medicine, Bristol Royal Infirmary.
BMJ—2004;328:215-216
To see the abstract of this article go to: http://www.bmj.com/content/328/7433/215

Diagnosis of Adrenal Insufficiency
Richard I. Dorin, MD; Clifford R. Qualls, PhD; and Lawrence M. Crapo, MD, PhD.
August 5, 2003 vol. 139 no. 3 194-204.
To see the abstract of this article go to: http://annals.org/aim/article/716603/diagnosis-adrenal-insufficiency

Combination therapy with hydrocortisone and fludrocortisone does not improve symptoms in chronic fatigue syndrome: a randomized, placebo-controlled, double-blind, crossover study
Daniel Blockmans, Philippe Persoons , Boudewijn Van Houdenhove , Marina Lejeune and Herman Bobbaers.
American Journal of Medicine – 15 June 2003, Volume 114, Issue 9 Pages 736-741.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/12829200

Small adrenal glands in chronic fatigue syndrome: a preliminary computer tomography study
Scott LV, Teh J, Reznek R, Martin A, Sohaib A, Dinan TG. Psychoneuroendocrinology.
Department of Psychiatry, Trinity College Dublin Medical School, St. James’s, Hospital, Ireland. 1999 Oct;24(7):759-68.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/10451910

Comparison of the Low Dose Short Synacthen Test (1µg), the Conventional Dose Short Synacthen Test (250µg), and the Insulin Tolerance Test for Assessment of the Hypothalamo-Pituitary -Adrenal Axis in Patients with Pituitary Disease
T.A.M. Abdu, T.A. Elhadd, R. Neary and R.N. Clayton.
Department of Endocrinology , North Staffordshire Hospitals, and School of Postgraduate Medicine, Keele University, Stoke on Trent, United Kingdom.
J Clin Endocrinol Metab. 1999 Mar;84(3):838-43.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/10084558

Shortcomings in the Low-Dose (1 μg) ACTH Test for the Diagnosis of ACTH Deficiency States
David H. P. Streeten.
Professor Emeritus of Medicine SUNY Health Science Center Syracuse, New York 13210.
March 1999.
To see the full text of this article go to: https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.84.3.5535

Adverse Drug Reactions

Risk of myocardial infarction in patients takingcyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis
Julia Hippisley-Cox and Carol Coupland.
BMJ 2005;330:1366 (11 June)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15947398

Non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death
Sabine M.J.M. Straus1,2,3, Miriam C.J.M. Sturkenboom1,2, Gysèle S. Bleumink1,4, Jeanne P. Dieleman1,2, Johan van der Lei2, Pieter A. de Graeff3,5, Jan Herre Kingma4,5 and Bruno H.Ch. Stricker1,4.
European Heart Journal Advance. Access originally published online on May 11, 2005.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15888497

Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients
Munir Pirmohamed, Sally James, Shaun Meakin, Chris Green,, Andrew K Scott, Thomas J Walley, Keith Farrar, B Kevin Park, Alasdair M Breckenridge.
1 Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE, 2 Royal Liverpool University Hospital, Liverpool L7 8XP, 3 Wirral Hospitals NHS Trust, Wirral CH49 5PE.
BMJ 2004;329:15-19 (3 July).
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15231615

Alzheimer’s Disease

Thyroid Function and the Risk of Alzheimer Disease – The Framingham Study
Zaldy S. Tan, M.D., M.P.H., Alexa Beiser, PhD, Ramachandran S. Vasan, M.D., Rhoda Au, PhD, Sanford Auerbach, M.D., Douglas P. Kiel, M.D., M.P.H., Philip A. Wolf, M.D., and Sudha Seshadri, M.D. (2008) Jul 28; 168(14): 1514–1520.
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694610/

Anaemia

Anemia: A Cause of Intolerance to Thyroxine Sodium
Capt K.M. Mohamed Shakir, MC, USNcorrespondence, Capt David Turton, MC, USN, Capt (SEL) Brian S. Aprill, MC, USN, Capt (SEL) Almond J. Drake III, MC, USN, Radm John F. Eisold, MC, USN.
Department of Internal Medicine, National Naval Medical Center and Uniformed Services University of the Health Sciences, Bethesda, Md.
February 2000 Volume 75, Issue 2, Pages 189–192.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/10683660

Bones, Skeletal, Osteoporosis

Long-term Risk of Incident Vertebral Fractures
Jane A. Cauley, DrPH; Marc C. Hochberg, MD, MPH; Li-Yung Lui, MA, MS; Lisa Palermo, MS; Kristine E. Ensrud, MD, MPH; Teresa A. Hillier, MD, MS; Michael C. Nevitt, PhD, MPH; Steven R. Cummings, MD.
JAMA. 2007;298(23):2761-2767.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18165669

Endocrine Regulation of Energy Metabolism by the Skeleton
Na Kyung Lee, Hideaki Sowa, Eiichi Hinoi, Mathieu Ferron, Jong Deok Ahn, Cyrille Confavreux, Romain Dacquin, Patrick J. Mee, Marc D. McKee, Dae Young Jung, Zhiyou Zhang, Jason K. Kim, Franck Mauvais-Jarvis, Patricia Ducy, and Gerard Karsenty.
2007 Aug 10;130(3):456-69.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17693256

Carbonated beverages and urinary calcium excretion
Robert P Heaney and Karen Rafferty.
Creighton University Osteoporosis Research Center, Omaha.
American Journal of Clinical Nutrition, Vol. 74, No. 3, 343-347, September 2001.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/11522558

Long-term Thyroxine Treatment and Bone Mineral Density
J.A. Franklin, J. Betteridge, J. Daykin, R. Holder, G.D. Oates, J.V. Parle, J. Lilley, D.A. Heath, M.C. Sheppard.
The Lancet. Vol. 340: 9-13, July 4, 1992.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/1351654

Cancer

Therapeutic Administration of 131I for Differentiated Thyroid Cancer: Radiation Dose to Ovaries and Outcome of Pregnancies
Jérôme-Philippe Garsi, Martin Schlumberger, Carole Rubino, Marcel Ricard, Martine Labbé, Claudia Ceccarelli, Claire Schvartz, Michel Henri-Amar, Stéphane Bardet and Florent de Vathaire.
Journal of Nuclear Medicine 2008;18:854-52.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18413399

Candida

In Vitro Killing of Candida Albicans by Fatty Acids and Monoglycerides
Cudmundur Bergsson, Johann Arnfinnsson, Olafur Steingrimsson and Halldor Thormar.
Antimicrobial Agents and Chemotherapy , November 2001, p. 3209-3212, Vol. 45, No. 11.
To see the full text of this article go to: http://aac.asm.org/content/45/11/3209.full

Central Hypothyroidism

Central Hypothyroidism: Pathogenic, Diagnostic, and Therapeutic Challenges
Luca Persani.
First Published Online: July 31, 2012 Journal of Clinical Endocrinology & Metabolism.
To see the full text of this article go to: https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2012-1616

CFS/ME

High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndrome
Thozhukat Sathyapalan, Stephen Beckett, Alan S Rigby, Duane D Mellor, Stephen L Atkin
Nutrition Journal 2010 9:55
To see the full text of this article go to: https://nutritionj.biomedcentral.com/articles/10.1186/1475-2891-9-55

Does hypocortisolism predict a poor response to cognitive behavioural therapy in chronic fatigue syndrome?
Roberts AD, Charler ML, Papadopoulos A, Wessely S, Chalder T, Cleare AJ.
King’s College London, Institute of Psychiatry, Department of Psychological Medicine, London, UK
Psychol Med. 2010 Mar;40(3):515-22. Epub 2009 Jul 17.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/19607750

Chronic Fatigue Syndrome is Associated with Chronic Enterovirus Infection of the Stomach
John K S Chia, Andrew Y Chia
J Clin Pathol 2007;0:1–6. doi: 10.1136/jcp.2007.050054
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17872383

Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome
N Kaushik, D Fear, S C M Richards, C R McDermott, E F Nuwaysir, P Kellam, T J Harrison, R J Wilkinson, D A J Tyrell, S T Holgate, J R Kerr.
J Clin Pathol 2005:58:826-832.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16049284

Fine-needle aspiration cytology of the thyroid in chronic fatigue
Bo Wikland, Torsten Löwhagen, P 0 Sandberg.
Hötorget Medical Centre, PO 1417, SE-11184 Stockholm, Sweden; and Department of Clinical Cytology, Medilab, PO Box 1550, Täby, Sweden (e-mail:bo.wikland@telia.com).
Volume 357, No. 9260, p956–957, 24 March 2001
To see the full text of this article go to: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)71654-8/fulltext

Small adrenal glands in chronic fatigue syndrome: a preliminary computer tomography study
Scott LV, Teh J, Reznek R, Martin A, Sohaib A, Dinan TG.
Department of Psychiatry, Trinity College Dublin Medical School, St. James’s, Hospital, Ireland. Psychoneuroendocrinology. 1999 Oct;24(7):759-68.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/10451910

Chemical Sensitivity

Developmental neurotoxicity of industrial chemicals
Dr, Prof P MD and PJ MD
The Lancet; 2006 Dec 16;368(9553):2167-2178
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17174709

Circadian rhythms of Thyroid Hormones

Free Triiodothyronine Has a Distinct Circadian Rhythm That Is Delayed but Parallels Thyrotropin Levels
Russell, R. F Harrison, N Smith, K. Darzy, S Shalet, A P Weetman, and R J Ross
J Clin Endocrinol Metab 93: 2300–2306, 2008
To see the full text of this article go to: https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2007-2674

Coeliac Disease and Thyroid

Coeliac disease in Dutch patients with Hashimoto’s thyroiditis and vice versa
Muhammed Hadithi, Hans de Boer, Jos WR Meijer, Frans Willekens, Jo A Kerckhaert, Roel Heijmans, Amado Salvador Peña, Coen DA Stehouwer and Chris JJ Mulder.
World J Gastroenterol. 2007 March. doi: 10.3748/wjg.v13.i11.1715.
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146952/

Diets

Weight and Metabolic Outcomes after 2 Years on a Low Carbohydrate Versus Low-Fat Diet – A Randomized Trail
G.D. Foster, H.R. Wyatt, J.O. Hill, A.P. Makris, D.L. Rosenbaum, C. Brill, R.I. Stein, B.S. Mohammed, B. Miller, D.J. Rader, B. Zemel, T.A. Wadden, T. Tenhave, C.W. Newcomb, and S. Klein.
Annals of Internal Medicine – Volume 153, pages 147-157. 2010 Aug 3
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/20679559

The Diet-Heart Hypothesis: A Critique by Sylvan Lee Weinberg, MD, MACC
(J Am Coll Cardiol 2004;43:731-3) © 2004 by the American College of Cardiology Foundation
To see the abstract of this article go to: http://www.onlinejacc.org/content/43/5/731

Drugs Affecting Levothyroxine

Drugs that interact with levothyroxine : an observational study from the Thyroid Epidemiology, Audit and Research Study (TEARS)
Savannah A. Irving, Thenmalar Vadiveloo and Graham P. Leese.
Clinical Endocrinology Volume 82, Issue 1, pages 136–141, January 2015.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/25040647

Altered intestinal absorption of L-thyroxine caused by coffee
Benvenga S, Bartolone L, Pappalardo MA, Russo A, Lapa D, Giorgianni G, Saraceno G, Trimarchi F.
2008 Mar;18(3):293-301.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18341376

Ciprofloxacin interacts with thyroid replacement therapy
John G Cooper endocrinologist , Knut Harboe, senior house officer, Sofia K Frost, pharmacist, Oyvind Skadberg, consultant physician. BMJ 2005;330:1002 (30 April)
To see the full text of this article go to: http://www.bmj.com/content/330/7498/1002.1

Variable Effects of Nonsteroidal Anti-inflammatory Agents on Thyroid Test Results
H. Samuels, K. Pillote, D. Asher and J. C. Nelson
The Journal of Clinical Endocrinology & Metabolism Vol. 88, No. 12 5710-5716
(2003)
To see the full text of this article go to: https://doi.org/10.1210/jc.2002-021869

Epstein-Barr virus

The role of Epstein-Barr virus infection in the development of autoimmune thyroid diseases
Janegova A, Janega P1, Rychly B, Kuracinova K, Babal P.
Endokrynologia Polska Sep 2015
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/25931043

Fibromyalgia

Lower Resting Metabolic Rate and Basal Body Temperature of Fibromyalgia Patients Compared to Matched Healthy Controls
John C. Lowe, Gina Honeyman-Lowe, Jackie Yellin
Thyroid Science 1(8):1-18, 2006
To see the full text of this article go to: http://www.thyroidscience.com/studies/lowe.2006/lowe.2nd.rmr.fm.study.pdf

Female Fibromyalgia Patients: Lower Resting Metabolic Rates Than Matched Healthy Controls
John C. Lowe, Gina Honeyman-Lowe, Jackie Yellin
Med Sci Monit, 2006; 12(7): CR282-289
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16810133?dopt=Abstract

Relief of Fibromyalgia Symptoms Following Discontinuation of Dietary Excitotoxins
Jerry D Smith, Chris M Terpening, Siegfried Of Schmidt, and John G Gums.
Annals of Pharmacotherapy: Vol. 35, No. 6, pp. 702-706. (June 2001)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/11408989

Effectiveness and safety of T3 (triiodothyronine) therapy for euthyroid fibromyalgia: a double-blind placebo-controlled response-driven crossover study
John C. Lowe, MA, DC, Richard L. Garrison, MD, Alan J. Reichman, MD, Jackie Yellin, BA, Mervianna Thompson, RN, MSN, APN, Daniel Kaufman, MD: Clinical Bulletin of Myofascial Therapy, 2(2/3):31-58, 1997.
To see the abstract of this article go to: http://www.tandfonline.com/doi/abs/10.1300/J425v02n02_04?journalCode=wzcb20

The process of change during T3 treatment for euthyroid fibromyalgia: a double-blind placebo-controlled crossover study
John C. Lowe, MA, DC, Alan J. Reichman, MD, Jackie Yellin, BA: Clinical Bulletin of Myofascial Therapy, 2(2/3):91-124, 1997.
To see the abstract of this article go to: http://www.tandfonline.com/doi/abs/10.1300/J425v02n02_07?journalCode=wzcb20

Triiodothyronine (T3) treatment of euthyroid fibromyalgia: a small-n replication of a double-blind placebo-controlled crossover study
John C. Lowe, MA, DC, DC, Richard L. Garrison, MD, Alan Reichman, MD, and Jackie Yellin, BA: Clinical Bulletin of Myofascial Therapy, 2(4):71-88, 1997.
To see the abstract of this article go to: http://www.tandfonline.com/doi/abs/10.1300/J425v02n04_05

Fluoride

A call for papers from EPA Standard for Fluoride in Drinking Water Is Not Protective Tooth Enamel Loss, Bone Fractures of Concern at High Levels
March 22, 2006
To see the statement go to: http://www8.nationalacademies.org/onpinews/newsitem.aspx?RecordID=s03222006

Bassin EB. (2001). Association between Fluoride in Drinking Water During Growth and Development and the Incidence of Osteosarcoma for Children and Adolescents
Doctoral Thesis, Harvard School of Dental Medicine.
To see the this article go to: http://www.fluoridealert.org/wp-content/uploads/bassin-2001.pdf

Foods affecting thyroid medications

Effects of grapefruit juice on the absorption of levothyroxine
Br J Clin Pharmacol. 2005 Sep;60(3):337-41.
Lilja JJ1, Laitinen K, Neuvonen PJ.
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884777/

Graves Disease

Relations of Thyroid Function to Body Weight: Cross-sectional and Longitudinal Observations in a Community-Based Sample
Caroline S. Fox, MD, MPH; Michael J. Pencina, PhD; Ralph B. D’Agostino, PhD; Joanne M. Murabito, MD; Ellen W. Seely, MD; Elizabeth N. Pearce, MD; Ramachandran S. Vasan, MD. Arch Intern Med. 2008; 168(6): 587-592.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18362250

Ultra Short-Loop Feedback Control of Thyrotropin Secretion
Mark F. Prummel, Leon J.S. Brokken, and Wilmar M. Wiersinga
THYROID, Volume 14, Number 10, 2004
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15588378

Excess radiation absorbed doses from non-optimised radioiodine treatment of hyperthyroidism
Jönsson H1, Mattsson S,
Radiat Prot Dosimetry. 2004;108(2):107-14.
To see the abstract of this paper go to: https://www.ncbi.nlm.nih.gov/pubmed/14978290

Suppression of Serum TSH by Graves’ Ig: Evidence for a Functional Pituitary TSH Receptor
Leon J. S. Brokken, Leon J. S. Brokken
Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands
J Clin Endocrinol Metab (2001) 86 (10): 4814-4817.
To see the full text of this article go to: https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.86.10.7922

Subclinical Hyperthyroidism

Thyroid Status, Cardiovascular Risk, and Mortality in Older Adults: The Cardiovascular Health Study
Anne R. Cappola, MD, ScM, Linda P. Fried, MD, MPH, Alice M. Arnold, PhD, Mark D. Danese, PhD, Lewis H. Kuller, MD, DrPH, Gregory L. Burke, MD, MS, Russell P. Tracy, PhD, and Paul W. Ladenson, MD JAMA. 2006 Mar 1; 295(9): 1033–1041.
To see the full text of this paper go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1387822/

Thyroid hormone therapy for older adults with subclinical hypothyroidism
David J. Stott et al
N Engl J Med. 2017 Jun 29;376(26):2534-2544
To see the full text of this paper go to: http://www.nejm.org/doi/full/10.1056/NEJMoa1603825

Hashimoto’s Disease

Effects of Prophylactic Thyroid Hormone Replacement in Euthyroid Hashimoto’s Thyroiditis
DY, Kerimoglu U, Okur H, Canpinar H, Karaagaoglu E, Yetgin S, Kansu E, Gedik O.
Section of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University. – Endocr. J. 2005 Jun; 52(3): 337-43
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16006728

Cardiac function in borderline hypothyroidism: a study by pulsed wave tissue Doppler imaging
Sandra Zoncu, Francesca Pigliaru1, Claudia Putzu1, Lorella Pisano, Sara Vargiu, Martino Deidda, Stefano Mariotti1 and Giuseppe Mercuro.
European Journal of Endocrinology, Vol 152, Issue 4, 527-533 (April 2005)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15817907

Effects of Prophylactic Thyroid Hormone Replacement in Euthyroid Hashimoto’s Thyroiditis
Duygu Yazgan Aksoy et. al.
Endocrine Journal (Japan) 2005, 52(3) 337-343
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16006728

Hypothyroidism

Hypothyroidism: Sensitive Diagnosis and Optimal Treatment of All Types and Grades – A Comprehensive Hypothesis
Based on a Review of the Standard and “Alternative” Literature and Extensive Clinical Experience.
John V. Dommisse, MD, MBChB, FRCP(C) (2008)
To see the full text of this article go to: http://www.thyroidscience.com/hypotheses/dommisse.feb.2008/dommisse.feb.2008.pdf

Relations of Thyroid Function to Body Weight: Cross-sectional and Longitudinal Observations in a Community-Based Sample
Caroline S. Fox, MD, MPH; Michael J. Pencina, PhD; Ralph B. D’Agostino, PhD; Joanne M Murabito MD; Ellen W Seely MD; Elizabeth N Pearce MD; Ramachandran S Vasan MD
Abstract summarised from: Arch Intern Med. 2008; 168(6): 587-592
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18362250

Sunscreen May Cause Hypothyroidism
The UV filter benzophenone 2 inactivates human recombinant thyroperoxidase in vitro and disturbs thyroid hormone homeostasis in rats
C Schmutzler1, A Bacinski1, P Ambrugger2, H Klammer3, W Wuttke3, A Grüters2, H Jarry3 & J Köhrle1.
Endocrine Abstracts (2006) 11 P429
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0011/ea0011p429.htm

Thyroid Hormone replacement therapy in primary hypothyroidism : a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone
Escobar-Morreale HF, Botella-CarreteroJI, Gomez-Bueno M, Galan JM, Barrios V,
Sancho J –Archives of Intern Med 2005 Mar 15;142(6)155
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15767619

The Birmingham Elderly Thyroid Study (BETS): TSH and fT4 values in 5784 community-living subjects aged 60 and over
JV Parle1, JA Franklyn2, S Wilson1, L Roberts1, R Holder1, MC Sheppard2, FDR Hobbs1, A Roalfe1, M Gammage2, C Heath1 & H Pattison 2005
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0009/ea0009p157.htm

The diagnosis and treatment of hypothyroidism: a patient’s perspective
Mel Row, Rudolf Hoermann, Peter Warmingham
The Diagnosis and Treatment of Hypothyroidism Issue 1 July 2016
To see this article go to: https://thyroiduk.org/tuk/TUK_PDFs/diagnosis_and_treatment_of_hypothyroidism_issue_1.pdf

Subclinical Hypothyroidism

Myxedema Coma in a Patient with Subclinical Hypothyroidism
Akhila Mallipedhi, Hamza Vali, and Onyebuchi Okosieme
THYROID Volume 21, Number 1, 2011
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/21058937

Clinical Case Report: Ultrastructural Evidence of Skeletal Muscle Mitochondrial Dysfunction in Patients with Subclinical Hypothyroidism
Michael E. Dunn,1 James V. Hennessey,2 Arthur C. Cosmas,1 Linda S. Lamont,1 and Thomas G. Manfredi1
Department of Kinesiology, University of Rhode Island, Kingston, Rhode Island 02881; 2Division of Endocrinology, Rhode Island Hospital, Brown University School of Medicine, Providence, Rhode Island 02912 (May 2009)
To see the abstract of this article go to: http://www.thyroidscience.com/cases/dunn.5.09/dunn.6.1.09.htm

Prevalence of Thyroid Dysfunction and Its Effect on Serum Lipid
Profiles in a Murzok, Libya Population
Ali M. Nouh, Ibrahim A. M. Eshnaf, and Mohamed A. Basher
Sebha University Faculty of Engineering and Technology Department of Medical Laboratory Sciences (2008)
To see the abstract of this article go to: http://www.thyroidscience.com/studies/nouh.08/libya.abstract10.08.htm

Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality
Ochs N1, Auer R, Bauer DC, Nanchen D, Gussekloo J, Cornuz J, Rodondi N.
Ann Intern Med. 2008 Jun 3;148(11):832-45. Epub 2008 May 19.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18490668

The association between TSH within the reference range and serum lipid concentrations in a population-based study. The HUNT Study
Bjørn O Åsvold1,2, Lars J Vatten1, Tom I L Nilsen1 and Trine Bjøro3
Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, N-7489 Trondheim, Norway, 2 St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway and 3 Department of Medical Biochemistry, Rikshospitalet-Radiumhospitalet Medical Center, Oslo, Norway
(June 2007)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17287407

The occurrence of permanent thyroid failure in patients with subclinical postpartum thyroiditis
Azizi European Journal of Endocrinology, Vol 153, Issue 3, 367-371
(2005)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16131598

Spontaneous Normalization of Thyrotropin Concentrations in Patients with Subclinical Hypothyroidism
Juan J. Díez, Pedro Iglesias and Kenneth D. Burman
The Journal of Clinical Endocrinology & Metabolism Vol. 90, No. 7 4124-4127 (July 2005)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15811925

Cardiac function in borderline hypothyroidism: a study by pulsed wave tissue Doppler imaging
Sandra Zoncu, Francesca Pigliaru1, Claudia Putzu1, Lorella Pisano, Sara Vargiu, Martino Deidda, Stefano Mariotti1 and Giuseppe Mercuro.
European Journal of Endocrinology, Vol 152, Issue 4, 527-533 (April 2005)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15817907

The effect of L-thyroxine replacement therapy on lipid-based cardiovascular risk in subclinical hypothyroidism
Serter R, Demirbas B, Korukluoglu B, Culha C, Cakal E, Aral Y Endocrinology and Metabolism, Ankara Education and Research Hospital, Ankara, Turkey.
Journal of Endocrinology Invest. 2004 Nov: 27(10):897-903
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15762035

Subchemical Hypothyroidism
Bo Wikland, P 0 Sandberg, Hans Wallinder
The Lancet Volume 357, Number 9260 24 March 2001
To see the full text of this article go to: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(03)13014-0/fulltext

Fine-needle aspiration cytology of the thyroid in chronic fatigue
Bo Wikland, Torsten Löwhagen, P 0 Sandberg
The Lancet Volume 357, No. 9260, p956–957, 24 March 2001
To see the full text of this article go to: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)71654-8/fulltext

Iodine

Potential Risks of Excess Iodine Ingestion and Exposure:
Statement by the American Thyroid Association Public Health Committee
Angela M. Leung, Anca M. Avram, Alina V. Brenner, Leonidas H. Duntas, Joel Ehrenkranz, James V. Hennessey, Stephanie L. Lee,7 Elizabeth N. Pearce, Sanziana A. Roman, Alex Stagnaro-Green, Erich M. Sturgis, Krishnamurthi Sundaram, Michael J. Thomas, and Jason A. Wexler
Thyroid. 2015 Feb 1; 25(2): 145–146.
To see the full text of this paper go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321767/

Effect of small doses of iodine on thyroid function in patients with Hashimoto’s thyroiditis residing in an area of mild iodine deficiency
W Reinhardt, M Luster, K H Rudorff, C Heckmann, S Petrasch, S Lederbogen, R Haase, B Saller, C Reiners, D Reinwein and K Mann.
European Journal of Endocrinology (1998) 139 23–28
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/9703374

Iron, Ferritin, Haem

Absorption of iron from ferritin is independent of heme iron and ferrous salts in women and rat intestinal segments
Theil EC1, Chen H, Miranda C, Janser H, Elsenhans B, Núñez MT, Pizarro F, Schümann K.
J Nutr. 2012 Mar; 142(3): 478–483. Published online 2012 Jan 18
To see the full text of this article go to: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278266/

Hypothyroidism and Depression
Colin M. Dayan and Vijay Panicker
Eur Thyroid J. 2013 Sep; 2(3): 168–179.
Published online 2013 Aug 27. doi: 10.1159/000353777 PMCID: PMC4017747
To see the full text of this article go to: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017747/

Thyroid hormones are associated with cognitive function: moderation by sex, race and depressive symptoms
A. Beydoun, PhD1, H. A. Beydoun, PhD2, M. H. Kitner-Triolo, PhD1, J. S. Kaufman, PhD3, M. K. Evans, MD1,† and A. B. Zonderman, PhD1,‡
J Clin Endocrinol Metab. 2013 Aug;98(8):3470-81
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/23690311

Thyroid hormones closely related to cognition in adults
Beydoun MA.
J Clin Endocrinol Metab. 2013;doi:10.1210/jc.2013-1813.June 4, 2013
To see the article go to: Http://www.healio.com/endocrinology/thyroid/news/online/%7BAB39C002-9760-47C2-BB3E-3AB2DF9C2F0C%7D/Thyroid-hormones-closely-related-to-cognition-in-adults

Thyroid hormones closely related to cognition in adults
Journal of Thyroid Research. 2012.
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321576/

Hypothyroidism Presenting as Psychosis: Myxedema Madness Revisited
Thomas W. Heinrich, M.D. and Garth Grahm, M.D.
J Clin Psychiatry. 2003
To see the full text of this article go to: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419396/

Psychiatric manifestations of Hashimoto’s thyroiditis
Richard C.W.Hall M.D., Michael K. Popkin M.D., Richard DeVaul M.D., Anne K Hall C.R.N.A., Earl R Gardener Ph.D., Thomas P. Beresford M.D
The Journal of the Academy of Psychosomatic Medicine 1982
To see the abstract of this article go to: http://www.psychosomaticsjournal.com/article/S0033-3182(82)73397-3/pdf?cc=y=

Myxoedematous Madness
Richard Asher M.D. M.R.C.P – Physician, Central Middlesex Hospital
British Medical Journal 1949
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2051123/

MS

Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease
Fernandez, M.
Proceedings of the National Academy of Sciences, Nov. 16, 2004; vol 101: pp 16363-16368.
To see the full text of this article go to: http://www.pnas.org/content/101/46/16363.full

Miscellaneous

Conjugated Equine Estrogen and Risk of Benign Proliferative Breast Disease:
A Randomized Controlled Trial
Thomas E. Rohan, Abdissa Negassa, Rowan T. Chlebowski, Laurel Habel, Anne McTiernan, Mindy Ginsberg, Sylvia Wassertheil-Smoller, David L. Page
JNCI Journal of the National Cancer Institute 2008 100(8):563-571;
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18398105

Mandatory disclosure of trial results for drugs and devices
Trish Groves, deputy editor
BMJ. 2008 Jan 26; 336(7637): 170.
To see this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213793/

A systematic review of randomised clinical trials of individualised herbal medicine in any indication
R Guo , P H Canter , E Ernst
Peninsula Medical School, Universities of Exeter & Plymouth, UK Correspondence to: Peter H Canter, Peninsula Medical School, Universities of Exeter & Plymouth, 25 Victoria Park Road, Exeter, EX2 4NT, UK
Postgraduate Medical Journal (Postgrad Med J 2007;83:633-637).
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600130/

Clinician attitudes toward biostatistics
West CP, Ficalora RD.
Mayo Clin Proc. 2007 Aug;82(8):939-43
To see the abstract of this paper go to: https://www.ncbi.nlm.nih.gov/pubmed/17673062?access_num=17673062&link_type=MED&dopt=Abstract

Genetic variation in deiodinases: a systematic review of potential clinical effects in humans
Herman Verloop, Olaf M Dekkers, Robin P Peeters, Jan W Schoones and Johannes W A Smit
European Journal of Endocrinology (2014) 171, R123–R135
To see this article go to: http://www.eje-online.org/content/171/3/R123.full.pdf

Calculated Parameters of Thyroid Homeostasis: Emerging Tools for Differential Diagnosis and Clinical Research
Johannes W. Dietrich, Gabi Landgrafe-Mend, Evelin Wiora, Apostolos Chatzitomaris, Harald H. Klein, John E. M. Midgley and Rudolf Hoermann
Front. Endocrinol., 09 June 2016
To see this article go to: http://journal.frontiersin.org/article/10.3389/fendo.2016.00057/full

Spurious Conclusions on Analog Free Thyroxine Assay Performance
Letter to the Editor by Dr John Midgley
Clinical Chemistry – Vol. 53, Issue 9 September 2007
To see this article go to: http://clinchem.aaccjnls.org/content/53/9/1714

Natural Desiccated Thyroid

Conversion to Armour Thyroid from Levothyroxine Improved Patient Satisfaction in the Treatment of Hypothyroidism
Gary M. Pepper* and Paul Y. Casanova-Romero
Gary M. Pepper, Palm Beach Diabetes and Endocrinology Specialists, University of Miami “Leonard M. Miller” School of Medicine, USA Published: 11 September 2014
To see the full text (pdf) of this article go to: https://www.jscimedcentral.com/Endocrinology/endocrinology-2-1055.pdf

Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study
Thanh D. Hoang, Cara H. Olsen, Vinh Q. Mai, Patrick W. Clyde, and Mohamed K. M. Shakir
J Clin Endocrinol Metab (2013) 98 (5): 1982-199
To see the full text of this article go to: https://doi.org/10.1210/jc.2012-4107

Improvements in quality of Life in Hypothyroid Patients taking Armour Thyroid
DH Lewis, J Kumar, P Goulden & DJ Barnes
Maidstone and Tunbridge Wells NHS Trust, Tunbrige Wells, Kent, UK
Endocrine Abstracts (2008).
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0015/ea0015p359.htm

Does synthetic thyroid extract work for everybody?
Gautam Das, Shweta Anand & Parijat De,
Diabetes & Endocrine Unit, City Hospital, Birmingham, United Kingdom.
Endocrine Abstracts (2007) 13 P316
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0013/ea0013P316.htm

Changes in Basal Metabolism, Serum-Protein-Bound Iodine and Cholesterol During Treatment of Hypothyroidism with Oral Thyroid and L-Thyroxine Sodium
DOUGLAS ROBERTSON, M.D., D.Sc., F.RC.P. F.R.I.C., D.P.H.,Director
and H. F. W. KIRKPATRICK, PhID., B.Sc., F.R.I.C.,
Chemical Pathologist, Department of Clinical Investigation, the London Clinic MARCH 22, 1952
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2023211/

Thyroid and Nutrition

Metabolic disorders and nutritional status in autoimmune thyroid diseases
Kawicka A1, Regulska-Ilow B1, Regulska-Ilow B1.
Postepy Hig Med Dosw (Online). 2015 Jan
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/25614676

Osteoporosis

Change of Bone Mineral Density and Biochemical Markers of Bone Turnover in Patients on Suppressive Levothyroxine Therapy for Differentiated Thyroid Carcinoma
Kim CW1, Hong S1, Oh SH1, Lee JJ2, Han JY1, Hong S1, Kim SH1, Nam M1, Kim YS1 J Bone Metab.
2015 August
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572035/

Pregnancy, Fertility & Children

Thyroid dysfunction and reproductive health
Jefferys A, Vanderpump M, Yasmin E. Thyroid dysfunction and reproductive health.
The Obstetrician & Gynaecologist 2015;17:39–45.
To see the full text of this article go to: http://onlinelibrary.wiley.com/enhanced/doi/10.1111/tog.12161/

Controversies in endocrinology: On the need for universal thyroid screening in pregnant women
Vila L1, Velasco I, González S, Morales F, Sánchez E, Torrejón S, Soldevila B, Stagnaro-Green A, Puig-Domingo M.
Eur J Endocrinol. 2013 Nov 29;170(1):R17-30. doi: 10.1530/EJE-13-0561. Print 2014 Jan.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/24128429

Measurement of total rather than free thyroxine in pregnancy: the diagnostic implications
Midgley JE, Hoermann R.
Thyroid. March 2013 doi: 10.1089/thy.2012.0469.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/23301702

Selective serotonin reuptake inhibitors in pregnancy and congenital malformations : population based cohort study
Pedersen LH, Henriksen TB, Vestergaard M, Olsen J, Bech BH.
Department of Epidemiology, Institute of Public Health, Aarhus University, Bartolin Allé 2, DK-8000 Aarhus, Denmark. LHP@dadlnet.dk
Obstet Gynecol. 2011 Jul;118(1):111-20.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/21646927

Maternal Thyroid Hormone Concentration During Late Gestation is Associated With Foetal Position at Birth
Hennie A Wijnen; Libbe Kooistra; Huib L Vader; Gerard G Essed; Ben W Mol; Victor J Pop
Clinical Endocrinology 2009; 71: 746-751
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/19320651

Prenatal and Postnatal Exposure to Cell Phone Use and Behavioral Problems in Children
Divan, Hozefa A.; Kheifets, Leeka; Obel, Carsten; Olsen, Jørn
Epidemiology. 2008 Jul;19(4):523-9.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18467962

Locomotor Deficiencies and Aberrant Development of Subtype-Specific GABAergic Interneurons Caused by an Unliganded Thyroid Hormone Receptor α1
Karin Wallis; Maria Sjögren; Max van Hogerlinden; Gilad Silberberg; André Fisahn; Kristina Nordström; Lars Larsson; Håkan Westerblad; Gabriela Morreale de Escobar; Oleg Shupliakov and Björn Vennström
The Journal of Neuroscience, 20 February 2008, 28(8): 1904-1915;
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/labs/articles/18287507/

Effect of levo-thyroxine treatment on weight and body mass index in children with acquired hypothyroidism
Lomenick JP, El-Sayyid MD, Smith WJ.
Division of Pediatric Endocrinology, University of Kentucky, Lexington, KY, USA.
J Pediatr.2008 Jan;152(1):96-100.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18154908

Therapeutic Administration of 131I for Differentiated Thyroid Cancer: Radiation Dose to Ovaries and Outcome of Pregnancies
Jérôme-Philippe Garsi, Martin Schlumberger, Carole Rubino, Marcel Ricard, Martine Labbé, Claudia Ceccarelli, Claire Schvartz, Michel Henri-Amar, Stéphane Bardet and Florent de Vathaire
Journal of Nuclear Medicine 2008;18:854-52
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18413399

Maternal Thyroid Autoantibodies during the Third Trimester and Hearing Deficits in Children: An Epidemiologic Assessment
Ellen E. Wasserman; Kenrad Nelson1; Noel R. Rose; William Eaton; Joseph P. Pillion; Eric Seaberg; Monica V. Talor; Lynne Burek; Anne Duggan; Robert H. Yolken
American Journal of Epidemiology 2008;167:701-710
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/18156602

Antepartum Dental Radiography and Infant Low Birth Weight
Philippe P. Hujoel, PhD; Anne-Marie Bollen, PhD; Carolyn J. Noonan, MS; Michael A. del Aguila, PhD
JAMA. 2004;291:1987-1993.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15113817

Thyroid autoimmunity and hypothyroidism before and during pregnancy
Kris Poppe and Daniel Glinoer
Human Reproduction Update, Vol.9, No.2 pp. 149±161, 2003
To read the full text of this article go to: https://doi.org/10.1093/humupd/dmg012

274 Maternal Thyroid Disease during Pregnancy and Subsequent Congenital Anomolies among Progeny
Adam J. Wolfberg, M.D., M.P.H.,
American Journal of Obstetrics Gynecology (2001)
To see the abstract of this article go to: http://www.ajog.org/article/S0002-9378(01)80307-0/abstract

When Thyroidologists Agree to Disagree: Comments on the 2012 Endocrine Society Pregnancy and Thyroid Disease Clinical Practice Guideline
Offie P. Soldin
The Journal of Clinical Endocrinology and Metabolism. 2012;97(8):2632-2635.
To see the article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410258/

Rhinitis

The relationship between hypothyroidism and rhinitis
Kulak Burun Bogaz Ihtis Derg. Günel C, Başak HS, Güney E.
Germencik Devlet Hastanesi Kulak Burun Boğaz Hastaliklari Kliniği, Aydin, Turkey.
2010 Jul-Aug;20(4):163-8.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/20626323

Selenium

Selenium supplementation for Hashimoto’s thyroiditis
Esther J van Zuuren1,*, Amira Y Albusta2, Zbys Fedorowicz3, Ben Carter4, Hanno Pijl5
Editorial Group: Cochrane Metabolic and Endocrine Disorders Group
(June 2016)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/23744563

Shared Decision Making

How should patients behave to facilitate shared decision making – the doctors’ view
Johannes Hamann MD1, Rosmarie Mendel PhD2, Markus Bühner PhD3, Werner Kissling MD4, Rudolf Cohen PhD5, Eva Knipfer Dr. rer. medic.6, Hans-Henning Eckstein MD7
2012 Dec;15(4):360-6.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/21624024

TSH Measurement and Its Implications for Personalised Clinical Decision-Making
Rudolf Hoermann1 and John E. M. Midgley2
Department of Nuclear Medicine, Klinikum Luedenscheid, Paulmannshoeherstraße 14, 58515 Luedenscheid, Germany
2Consultancy Division, North Lakes Clinical, 6 High Wheatley, Ilkley, West Yorkshire LS29 8RX, UK ( 5 October 2012)
To see the full text of this article go to: http://www.hindawi.com/journals/jtr/2012/438037/

Smoking and the thyroid

The association of cigarette smoking with serum TSH concentration and thyroperoxidase antibody
Mehran L, Amouzgar A, Delshad H, Azizi F.
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Exp Clin Endocrinol Diabetes. 2012 Feb;
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/21915816

Weight Gained after Smoking Cessation May Be Caused by Onset of Hypothyroidism
Jorge H. Mestman
Clin Thyroidol 2012;24:10–11
To see the full text (pdf) of this article go to: https://www.thyroid.org/wp-content/uploads/publications/clinthy/volume24/issue12/clinthy_v2412_10_11.pdf

Smoking May Decrease the Incidence of Thyroid Cancer in Postmenopausal Women
Jerome M. Hershman
Clin Thyroidol 2012;24:8–9
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/22525339

Free triiodothyronine is associated with smoking habit, independently of obesity, body fat distribution, insulin, and metabolic parameters
De Pergola G, Ciampolillo A, Alò D, Sciaraffia M, Guida P.
Source Internal Medicine, Endocrinology, Andrology, and Metabolic Disease, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Policlinico, Via Putignani 236, Bari, Italy.
J Endocrinol Invest. 2010 Dec;33(11):815-8. doi: 10.3275/7168. Epub 2010 Jul 13.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/20634638

Tobacco Smoking and Thyroid Function
Bjørn O Åsvold, MD; Trine Bjøro, MD PhD; Tom I. L Nilsen, PhD; Lars J. Vatten, MD, PhD
Arch Intern Med. 2007;167(13):1428-1432.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17620538

Impact of smoking on the course of Graves’ disease after withdrawal of antithyroid drugs
Quadbeck B, Roggenbuck U, Janssen OE, Hahn S, Mann K, Hoermann R
Exp Clin Endocrinol Diabetes. Sept 2006 doi: 10.1055/s-2006-924065
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/17039420

T3

Low-T3 Syndrome – A Strong Prognostic Predictor of Death in Patients With Heart Disease
Giorgio Iervasi MD; Alessandro Pingitore MD, PhD; Patrizia Landi BSc; Mauro Raciti BSc;
Andrea Ripoli PhD; Maria Scarlattini BSc; Antonio L’Abbate MD; Luigi Donato MD
To see the full article go to: http://circ.ahajournals.org/content/107/5/708

Is a Normal TSH Synonymous with “Euthyroidism” in Levothyroxine Monotherapy?
Sarah J. Peterson Ph.D., Elizabeth A. McAninch M.D., and Antonio C. Bianco M.D.
J Clin Endocrinol Metab. 2016 Dec;101(12):4964-4973.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/27700539

Liothyronine use in a 17-year observational population-based study – the tears study
Graham Leese – grahamleese@nhs.net; Enrique Soto-Pedre, Louise A. Donnelly
First published: 21 March 2016 DOI: 10.1111/cen.13052
To see the abstract of this article go to: http://onlinelibrary.wiley.com/doi/10.1111/cen.13052/full

New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism
Elizabeth A McAninchemail, Antonio C Bianco
Published: 08 September 2015.
To see the abstract of this article go to: http://www.thelancet.com/journals/landia/article/PIIS2213-8587(15)00325-3/fulltext

Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects
Hoermann R1, Midgley JE2, Larisch R1, Dietrich JW3.
Horm Metab Res. 2015 Mar 6.
To see the abstract of this article go to: https://www.thieme-connect.com/DOI/DOI?10.1055/s-0034-1398616

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine
Joao Pedro Werneck de Castro1,2, Tatiana L. Fonseca1,2, Cintia B. Ueta1, Elizabeth A. McAninch1,2, Sherine Abdalla1, Gabor Wittmann3, Ronald M. Lechan3, Balazs Gereben4 and Antonio C. Bianco1,2.
First published January 2, 2015.
To see the abstract of this article go to: http://www.jci.org/articles/view/77588

Safety review of liothyronine use: a 20 year observational follow up study
Enrique Soto-Pedre & Graham Leese
(2015)
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0038/ea0038OC5.6.htm

Conversion to Armour Thyroid from Levothyroxine Improved Patient Satisfaction in the Treatment of Hypothyroidism
Gary M. Pepper* and Paul Y. Casanova-Romero.
Published: 11 September 2014.
To see the abstract of this article go to: www.jscimedcentral.com/Endocrinology/endocrinology-2-1055.pdf

Paradigm shifts in thyroid hormone replacement therapies for hypothyroidism
Wilmar M. Wiersinga.
2014 Mar;10(3):164-74
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/24419358

Treatment with Thyroid Hormone
Bernadette Biondi and Leonard Wartofsky.
2014 Jun;35(3):433-512
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/24433025

Combination Treatment with T4 and T3: Toward Personalized Replacement Therapy in Hypothyroidism?
Bernadette Biondi, and Leonard Wartofsky.
J Clin Endocrinol Metab. 2012 Jul;97(7):2256-71.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/22593590

The pharmacodynamic equivalence of levothyroxine and liothyronine. A randomized, double-blind, cross-over study in thyroidectomized patients
Francesco S Celi1, Marina Zemskova2, Joyce D Linderman1, Nabeel I. Babar1, Monica C
Skarulis1, Gyorgy Csako3, Robert Wesley4, Rene Costello3, Scott R Penzak5, and Frank Pucino5.
Clin Endocrinol (Oxf). 2010 May ; 72(5): 709–715.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888764/pdf/nihms146786.pdf

Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination T4/T3 therapy in patients on thyroid hormone replacement
Vijay Panicker, Ponnusamy Saravanan, Bijay Vaidya, Jonathan Evans, Andrew T. Hattersley, Timothy M. Frayling and Colin M. Dayan.
The Journal of Clinical Endocrinology & Metabolism Vol. 94, No. 5 1623-1629 (2009)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/19190113

Free Triiodothyronine Has A Distinct Circadian Rhythm That Is Delayed But Parallels Thyrotrophin Levels
W Russell*: R. F. Harrison*:
N Smith: K Darzy: S Shalet: A P Weetman: R J Ross (corresponding Author):
* These two Authors made equal contributions.
Clin Endocrine Metab. First published ahead of print March 25, 2008 as doi:10.1210/jc.2007-2674.
To see the abstract of this article go to: https://doi.org/10.1210/jc.2007-2674

Improvements in quality of Life in Hypothyroid Patients taking Armour thyroid
DH Lewis, J Kumar, P Goulden & DJ Barnes.
(2008)
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0015/ea0015p359.htm

Supraphysiological cyclic dosing of sustained release T3 in order to reset low basal high temperature
Friedman M, Miranda-Massari JR, Gonzalez MJ. Puerto Rico Health Sciences Journal 2006 Mar;25(1):23-9.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16883675

Thyroid Hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone
Escobar-Morreale HF, Botella-CarreteroJI, Gomez-Bueno M, Galan JM, Barrios V, Sancho J – Archives of Intern Med 2005 Mar 15;142(6)155.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15767619

Combined Therapy with Levothyroxine and Liothyronine in Two Ratios, Compared with Levothyroxine Monotherapy in Primary Hypothyroidism: a Double-Blind, Randomized, Controlled Clinical Trial
Bente C. Appelhof, Eric Fliers, Ellie M. Wekking, Aart H. Schene, Jochanan Huyser, Jan G. P. Tijssen, Erik Endert, Henk C. P. M. van Weert and Wilmar M. Wiersinga. The Journal of Clinical Endocrinology & Metabolism Vol. 90, No. 5 2666-2674 (May 2005)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15705921

T3/T4 Combination Therapy
AD Toft. (2002)
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0003/ea0003s40.htm

Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat
Escobar-Morreale HF1, del Rey FE, Obregón MJ, de Escobar GM.
Endocrinology. 1996 Jun;137(6):2490-502.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/8641203

Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats
H F Escobar-Morreale, M J Obregón, F Escobar del Rey, and G Morreale de Escobar.
J Clin Invest. 1995 Dec; 96(6): 2828–2838.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC185993/

Changes in Serum Triiodothyronine (T3) Kinetics after Prolonged Antarctic Residence: The Polar T3 Syndrome
Lester Reed, Eugene D. Silverman, K. M. Mohamed Shakir, Robert Dons, Kenneth D. Burman, And John T. O’brian.
Received: April 14, 1989 First Published Online: July 01, 2013
To see the abstract of this article go to: https://academic.oup.com/jcem/article-abstract/70/4/965/2652582/Changes-in-Serum-Triiodothyronine-T3-Kinetics?redirectedFrom=fulltext

Levothyroxine overuse: time for an about face?
Rene Rodriguez-Gutierrez, Spyridoula Maraka, Naykky Singh Ospina, Naykky Singh Ospina, Victor M Montori, Juan P Brito
The Lancet Volume 5, No. 4, p246–248, April 2017
http://www.thelancet.com/journals/landia/article/PIIS2213-8587(16)30276-5/abstract

DIAGNOSIS OF ENDOCRINE DISEASE: How reliable are free thyroid and total T3 hormone assays?
Kerry J Welsh and Steven J Soldin
Eur J Endocrinol December 1, 2016 175 R255-R263
To see the article go to: http://www.eje-online.org/content/175/6/R255.full

Testing

Validity of Analog Free Thyroxin Immunoassays. Part II
John E. M. MIdgiey,Carl R. Moon and Terence A. Wilkins
Clinical Chemistry – Vol. 33, No. 12, 1987
To see the article go to: http://clinchem.aaccjnls.org/content/33/12/2145

Pitfalls in the measurement and interpretation of thyroid function tests
Olympia Koulouri, MRCP, NIHR Academic Clinical Fellow,a Carla Moran, MRCPI, Senior Clinical Fellow,a David Halsall, PhD, FRCPath, Consultant Clinical Scientist,b Krishna Chatterjee, FRCP, Professor of Endocrinology,a and Mark Gurnell, PhD, FRCP, Senior Lecturer in Endocrinology & Associate Clinical Deana,c,∗
Best Pract Res Clin Endocrinol Metab. 2013 Dec; 27(6): 745–762.
To see the article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857600/

Is it safe for patients taking thyroxine to have a low but not suppressed serum TSH concentration?
Graham Leese & Robert Flynn
University of Dundee, Tayside, UK
Endocrine Abstracts (2010) 21 OC5.6
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0021/ea0021OC5.6.htm

The Evidence for a Narrower Thyrotropin Reference Range Is Compelling
Leonard Wartofsky and Richard A Dickey
Department of Medicine, Washington Hospital Center, Washington, D.C. 20010; Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814; and Georgetown University School of Medicine, Washington, D.C. 20006
Journal of Clinical Endocrinology and Metabolism (2005)Vol. 90, No. 9 5483-5488
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16148345

Thyroid Medications

Safety review of liothyronine use: a 20-year observational follow-up study
Enrique Soto-Pedre & Graham Leese
Endocrine Abstracts (2015) 38 OC5.6 | DOI:10.1530/endoabs.38.OC5.6
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0038/ea0038OC5.6.htm

New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism
Elizabeth A McAninchemail, Antonio C Bianco
The Lancet – Diabetes & Endocrinology Volume 3, No. 10 08 September 2015
To see the full article go to: http://thelancet.com/journals/landia/article/PIIS2213-8587(15)00325-3/fulltext

UK Trends in Prescribing Thyroid Hormone and Patient Satisfaction Survey
AL Mitchell1, B Hickey2, JL Hickey2 & SHS Pearce1
Abstract taken from: Endocrine Abstracts (2009) 19 P345
To see the abstract of this article go to: www.endocrine-abstracts.org/ea/0019/ea0019p345.htm

Improvements in quality of Life in Hypothyroid Patients taking Armour thyroid
DH Lewis, J Kumar, P Goulden & DJ Barnes
Maidstone and Tunbridge Wells NHS Trust, Tunbrige Wells, Kent, UK.
Abstract taken from :Endocrine Abstracts (2008) 15 P359
To see the abstract of this article go to: www.endocrine-abstracts.org/ea/0015/ea0015p359.htm

Tablet-splitting: a common yet not so innocent practice
Charlotte Verrue, Els Mehuys, Koen Boussery, Jean-Paul Remon & Mirko Petrovic
Journal of Advanced Nursing 67(1), 26–32. doi: 10.1111/j.1365-2648.2010.05477.x June (2008)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/21158902

Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients
Bolk, Nienke1; Visser, Theo J.1; Kalsbeek, Andries2; van Domburg, Ron T.3; Berghout, Arie4
Clinical Endocrinology, Volume 66, Number 1, January 2007 , pp. 43-48(6)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/17201800

Bioequivalence of L-thyroxine tablets and a liquid L-thyroxine solution in the treatment of hypothyroid patients
Grussendorf M, Vaupel R, Wegscheider K.
Med Klin (Munich). 2004 Nov 15;99(11):639-44.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15583873

Biochemical Markers Reflecting Thyroid Function in Athyreotic Patients on Levothyroxine Monotherapy
Mitsuru Ito, Akira Miyauchi, Mako Hisakado, Waka Yoshioka, Akane Ide, Takumi Kudo, Eijun Nishihara, Minoru Kihara, Yasuhiro Ito, Kaoru Kobayashi, Akihiro Miya, Shuji Fukata, Mitsushige Nishikawa, Hirotoshi Nakamura, and Nobuyuki Amino
Thyroid. 2017 Apr 1; 27(4): 484–490.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385443/

Dual control of pituitary thyroid stimulating hormone secretion by thyroxine and triiodothyronine in athyreotic patients
Rudolf Hoermann, Johannes W. Dietrich, Rolf Larisch
Therpeutic Advances in endocrinology and metabolism. Volume: 8 issue:6, page(s): 83-95
To see this article go to: http://journals.sagepub.com/doi/full/10.1177/2042018817716401

Thyroidectomy

Five-year follow-up for a randomised clinical trial of unilateral thyroid lobectomy with or without postoperative levothyroxine treatment
Barczynski M, Konturek A, Golkowski F, et al World J Surg.
2010 Jun;34(6):1232-8.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/20130863

TSH

Homeostatic Control of the Thyroid–Pituitary Axis: Perspectives for Diagnosis and Treatment
Rudolf Hoermann1, John E. M. Midgle2y, Rolf Larisch1 and Johannes W. Dietrich3,4
Front. Endocrinol., 20 November 2015
To see the full article go to: http://journal.frontiersin.org/article/10.3389/fendo.2015.00177/full#h1

Reference range for thyrotropin. Post hoc assessment
Larisch1; A. Giacobino1; W. Eckl1; H.-G. Wahl2; J. E. M. Midgley3; R. Hoermann1
1Klinik für Nuklearmedizin, Klinikum Lüdenscheid, Germany; 2Institut für Laboratoriumsmedizin, Klinikum Lüdenscheid, Germany; 3North Lakes Clinical, Ilkley, UK
Nuklearmedizin. 2015;54(3):112-7.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/25567792

Does fasting or postprandial state affect thyroid function testing?
Rakesh Nair, Shriraam Mahadevan,1 R. S. Muralidharan, and S. Madhavan
Indian J Endocrinol Metab. 2014 Sep-Oct; 18(5): 705–707.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/25285290

Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment
Rudolf Hoermann*, John E.M. Midgley†, Adrienne Giacobino*, Walter A. Eckl*, Hans G€unther Wahl‡, Johannes W. Dietrich§ and Rolf Larisch*
*Department of Nuclear Medicine, Klinikum Luedenscheid, Luedenscheid, Germany, †North Lakes Clinical, Ilkley, UK, ‡Institute for Laboratory Medicine, Klinikum Luedenscheid, Luedenscheid, and §Medical Department I, Endocrinology and Diabetology, Ruhr University of Bochum, Bochum, Germany Clinical Endocrinology (2014)
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/24953754

Is pituitary TSH an adequate measure of thyroid hormone-controlled homoeostasis during thyroxine treatment?
Hoermann R, Midgley JE, Larisch R, Dietrich JW.
Department of Nuclear Medicine, Klinikum Luedenscheid, Paulmannshoeher Street 14, D-58515 Luedenscheid, Germany. rudolf.hoermann@gmail.com
Eur J Endocrinol. 2013 Jan 17;168(2):271-80. doi: 10.1530/EJE-12-0819. Print 2013 Feb.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/23184912

Is it safe for patients taking thyroxine to have a low but not suppressed serum TSH concentration?
Graham Leese & Robert Flynn
University of Dundee, Tayside, UK Endocrine Abstracts (2010) 21 OC5.6
To see the abstract of this article go to: http://www.endocrine-abstracts.org/ea/0021/ea0021oc5.6.htm

TSH may not be a good marker for adequate thyroid hormone replacement therapy
Wien Klin Wochenschr.Alevizaki M, Mantzou E, Cimponeriu AT, Alevizaki CC, Koutras DA.
Endocrine Unit, Dept Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Athens, Greece. 2005 Sep;117(18):636-40.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16416346

Does normal TSH mean euthyroidism in L-T4 treatment (Summary)
Orgiazzi Jacques.
Clinical Thyroidology. November 2016, 28(11): 325-328.
To see the article go to: http://online.liebertpub.com/doi/abs/10.1089/ct.2016%3B28.325-328?journalCode=ct

The relationship between TSH and free T4 in a large population is complex, non-linear and differs by age and gender
Narelle C. Hadlow, Karen M. Rothacker, Robert Wardrop, Suzanne J. Brown, Ee Mun Lim, John P. Walsh
The Journal of Clinical Endocrinology & Metabolism, Volume 98, Issue 7, 1 July 2013, Pages 2936–2943,
To see the article go to: https://academic.oup.com/jcem/article/98/7/2936/2537137/The-Relationship-Between-TSH-and-Free-T4-in-a

Thyroid and Colour Vision

Cone photoreceptors and potential UV vision in a subterranean insectivore, the European mole
Martin Glösmann; Marianne Steiner; Leo Peichl; Peter K. Ahnelt
Journal of Vision April 2008, Vol.8, 23. March 29, 2011
To see the full article go to: http://jov.arvojournals.org/article.aspx?articleid=2122378
To see a report of this article go to: https://www.mpg.de/1322093/thyroid_affects_colour_vision

Vitamin B12 / Pernicious Anaemia

Obsessive-Compulsive Disorder as Early Manifestation of B12 Deficiency
Indian J Psychol Med.
2011 Jul-Dec; 33(2): 203–204
To see the full article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271502/

Prevalence and evaluation of B12 deficiency in patients with autoimmune thyroid disease
Ness-Abramof R, Nabriski DA, Braverman LE, Shilo L, Weiss E, Reshef T, Shapiro MS, Shenkman L.
Endocrine Unit, Sapir Medical Center, Tchernikovsky 53, Kfar Saba, Israel 44261. Rosane-Abramof.Ness@clalit.org.il
Am J Med Sci. 2006 Sep;332(3):119-22.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/16969140

[Psychiatric manifestations of vitamin B12 deficiency: a case report]
Encephale. 2003 Nov-Dec;29(6):560-5.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/15029091

Vitamin D

Vitamin D Deficiency and Its Association with Thyroid Disease
Dr. Amal Mohammed Husein Mackawy,(1) Bushra Mohammed Al-ayed,(2) and Bashayer Mater Al-rashidi(3)
Int J Health Sci (Qassim). Nov 2013; 7(3): 267–275.
To see the full text of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271502/

Our Advisers’ Research

Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease
Midgley JE, Hoermann R, Larisch R, Dietrich JW.
Eur Thyroid J. 2016 Sep;5(3):171-179. Epub 2016 Aug 18.
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/27843807

Derivation of a Multivariate Reference Range for Pituitary Thyrotropin and Thyroid Hormones: Diagnostic Efficiency Compared to Conventional Single Reference Method
Rudolf Hoermann, Rolf Larisch, Johannes W Dietrich and John E M Midgley.
Eur J Endocrinol. 2016 Jun;174(6):735-43. doi: 10.1530/EJE-16-0031. Epub 2016
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pubmed/26951601

An article in The Lancet
Of rats and men: thyroid homeostasis in rodents and human being
Johannes W Dietrichemail, John E M Midgley, Rolf Larisch, Rudolf Hoermann.
Published: December 2015 Volume 3, No. 12, p932–933
To see the abstract of this article go to: http://www.thelancet.com/journals/landia/article/PIIS2213-8587(15)00421-0/fulltext

The role of thyroid hormones in anxiety and depression
Larisch1, S. Schulte1, G. Hildenbrand2, R. Hörmann.
April 2015
To see the abstract of this article go to: www.nuklearmedizin.de/jahrestagungen/abstr_online2015/abstract_detail.php?navId=162&aId=78

Variation in the Biochemical Response to L-Thyroxine Therapy and Relationship with Peripheral Thyroid Hormone Conversion
John E M Midgley, Rolf Larisch, Johannes W Dietrich and Rudolf Hoermann.
Published 2015, doi: 10.1530/EC-15-0056
To see the abstract of this article go to: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557078/

Hypothalamus-pituitary-thyroid feedback control: implications of mathematical modeling and consequences for thyrotropin (TSH) and free thyroxine (FT4) reference ranges
Goede SL, Leow MK, Smit JW, Klein HH, Dietrich JW.
Bull Math Biol. 2014 Jun;76(6):1270-87. doi: 10.1007/s11538-014-9955-5.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/24789568

17TSH Measurement and Its Implications for Personalised Clinical Decision-Making
Hoermann R, Midgley JE.
Journal of Thyroid Research, 2012.
To see this article go to: http://www.ncbi.nlm.nih.gov/pubmed/23304636

A novel minimal mathematical model of the hypothalamus-pituitary-thyroid axis validated for individualized clinical applications
Goede SL, Leow MK, Smit JW, Dietrich JW.
Math Biosci. 2014 Mar;249:1-7. doi: 10.1016/j.mbs.2014.01.001. Epub 2014 Jan 28..
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/24480737

Do thyroid-stimulating hormone, body weight, or body mass index serve as adequate markers to guide levothyroxine dose titration?
Dietrich JW, Leow MK, Goede SL, Midgley JE, Landgrafe G, Hoermann R.
J Am Coll Surg. 2013 Oct;217(4):752-3. doi: 10.1016/j.jamcollsurg.2013.06.008.
To see the abstract of this article go to: http://www.researchgate.net/publication/256928352

Measuring thyroid peroxidase antibodies on the day nulliparous women present for management of miscarriage: a descriptive cohort study
Grossmann M, Hoermann R, Francis C, Hamilton EJ, Tint A, Kaitu’u-Lino T, Kuswanto K, Lappas M, Sikaris K, Zajac JD, Permezel M, Tong S.
Reprod Biol Endocrinol. 2013 May 14;11:40. doi: 10.1186/1477-7827-11-40.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/23672306

Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model
Midgley JE, Hoermann R, Larisch R, Dietrich JW.
J Clin Pathol. 2013 Apr;66(4):335-42. doi: 10.1136/jclinpath-2012-201213. E
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/23423518

TSH and Thyrotropic Agonists: Key Actors in Thyroid Homeostasis
Dietrich JW, Landgrafe G, Fotiadou EH.
J Thyroid Res. 2012;2012:351864. doi: 10.1155/2012/351864. Epub 2012 Dec 30.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/23365787

The parathyroid as a target for radiation damage
Boehm BO, Rosinger S, Belyi D, Dietrich JW.
N Engl J Med. 2011 Aug 18;365(7):676-8. doi: 10.1056/NEJMc1104982.
To see the abstract of this article go to: http://www.nejm.org/doi/full/10.1056/NEJMc1104982

“All that glisters is not gold”: Ultrafiltration and free thyroxine measurement With apologies to W Shakespeare
Midgley JE.
Clin Biochem. 2011 Feb;44(2-3):151-3. doi: 10.1016/j.clinbiochem.2010.11.001. Epub 2010 Nov 11.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/21074522

Complex relationship between free thyroxine and TSH in the regulation of thyroid function
Hoermann R, Eckl W, Hoermann C, Larisch R.
Eur J Endocrinol. June 2010 doi: 10.1530/EJE-10-0106
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/20299491

Thyroxine in goiter, H. pylori infection, and gastritis
Dietrich JW, Boehm BO
N Engl J Med. 2006 Sep 14;355(11):1177; author reply 1177.
To see the letter and response go to: https://www.ncbi.nlm.nih.gov/pubmed/16641395

Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations
Gärtner R, Gasnier BC, Dietrich JW, Krebs B, Angstwurm MW.
J Clin Endocrinol Metab. 2002 Apr;87(4):1687-91.
To see the abstract of this article go to: http://www.ncbi.nlm.nih.gov/pubmed/11932302

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