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Research Articles and Papers on:



In Vitro Killing of Candida Albicans by Fatty Acids and Monoglycerides

Cudmundur Bergsson, Johann Arnfinnsson, Olafur Steingrimsson and Halldor Thormar

Antimicrobial Agents and Chemotherapy, November 2001, p. 3209-3212, Vol. 45, No. 11

These researchers state, Candida albicans is normally present in small numbers in the oral cavity, lower gastrointestinal tract, and female genital tract.” They tell us that most candida albicans infections are caused internally except in cases of direct contact with lesions, for example, through sexual intercourse and that it can produce “diseases ranging from superficial skin or mucous membrane infections, e.g., oral lesions called thrush and vaginal candidiasis, to systemic involvement of multiple organs. Infections are often a complication of broad-spectrum antibacterial therapy.” 
They explain that medium-chain free fatty acids and their corresponding 1-monoglycerides have been found to be effective against diseases like herpes simplex virus, gonorrhoeae, chlamydia, streptococci and staphylococcus in vitro (test tubes etc).

How this happens is not known but microscope studies show that they disrupt cell membranes. The lipids are commonly found in natural products such as milk. 
These compounds are considered to be potent inhibitors of many human pathogens or parasites in milk and in mucosas (mucous membranes).     

This research was done to find out if some fatty acids or their 1-monoglycerides might inactivate Candida albicans and therefore be useful for treatment of skin infections and mucosas caused by this.

They looked at the susceptibility of Candida albicans to several fatty acids and their 1-monoglycerides and ultrathin sections were studied by transmission electron microscopy (TEM) after treatment with capric acid. The researchers concluded, “The results show that capric acid, a 10-carbon saturated fatty acid, causes the fastest and most effective killing of all three strains of C. albicans tested, leaving the cytoplasm disorganized and shrunken because of a disrupted or disintegrated plasma membrane. Lauric acid, a 12-carbon saturated fatty acid, was the most active at lower concentrations and after a longer incubation time.

This goes to show that taking your Coconut Oil, which is full of lauric acid, a Medium Chain Fatty Acid, can help immensely with candida albicans.